Grey's Anatomy Season 2 Episode 19
What Have I Done to Deserve This?
Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what's up. Derek and Addison are experiencing their own version of morning-after tension as a result of Mark's visit to Seattle. Bailey, returning the favor that was done for her during the Code Black situation, must treat Addison for a specific feminine problem. Izzie and Alex are making headway in their relationship until Denny Duquette comes back. Soon Alex is not-so-oddly jealous of the attention Izzie is showing to Denny. Someone finds comfort in confiding in a patient who is going through an ordeal of his own. Burke deals with a patient and gets to observe the patient's unstable relationship with his fiancée.
Guest Stars

Sara Ramirez
Callie Torres

Matt Roth
Michael Beglight

Mark Harelik
Keith Polace

Cress Williams
Tucker Jones

Jeremy Rabb
Resident