Grey's Anatomy Season 4 Episode 16
Freedom
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.
Guest Stars
Brooke Smith
Erica Hahn
Jurnee Smollett-Bell
Beth Monroe
Loretta Devine
Adele Webber
Amy Madigan
Katharine Wyatt
Lauren Stamile
Nurse Rose